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Heim›Dengue NS1 antigen, IgG and IgM
Testdetail
general description
interpretation of the results
Frequently Asked Questions
tests included
Content created by
Written by
dr AS female chandoli
BDS, MDS - Oral Pathology and Microbiology
reviewed by
DR. Ashish Ranjan
MBBS, MD (Pharmacology)
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Dengue NS1 antigen, IgG and IgM
The exam includes
3
prove
SSee everything
you need to provide
Sangre
This test is for
Male Female
exam preparation
- Requires no special preparation
general description
What is Dengue NS1 Antigen, IgG and IgM?
The Dengue Antigen NS1, IgG, and IgM test detects the nonstructural protein component (NS1) of dengue virus and the antibodies (IgG and IgM) produced by the body in response to infection. NS1 and IgM are secreted into the blood during dengue infection and are detectable within 3-4 days of illness. Therefore, this test helps in the early detection and treatment of dengue infection. IgG antibodies appear after day 14 of infection and persist for life.
Initial symptoms that are common with dengue include a sudden high fever, fatigue, and flu-like symptoms.
If left untreated, the infection can progress to severe forms such as dengue hemorrhagic fever or dengue shock syndrome.
Why is Dengue Antigen NS1, IgG and IgM performed?
Dengue antigen NS1, IgG and IgM test is performed when high fever occurs within 2 weeks of travel to an area where dengue outbreak is occurring or when dengue fever is endemic.
What do Dengue NS1 antigen, IgG and IgM measure?
The Dengue NS1, IgG and IgM antigen test measures dengue virus or antibodies produced in response to dengue infection. Dengue is a viral infection transmitted to humans by mosquitoes that live in tropical and subtropical climates and are responsible for transmitting the virus.
According to the Centers for Disease Control and Prevention (CDC), dengue infections have been reported in more than 100 countries in parts of Africa, the Americas, the eastern Mediterranean, the western Pacific Caribbean and Southeast Asia.
According to the WHO (World Health Organization), dengue is a rapidly onset infectious disease. The number of cases and countries affected by dengue is increasing significantly. With 75% of cases showing no symptoms, the true number is unknown, but the annual number of dengue infections reaches approximately 390 million.
Most affected people develop no symptoms or only mild illness when exposed to any of the four dengue virus serotypes. Should a patient develop symptoms, the prognosis is good for a full recovery within a few weeks.
Common initial symptoms are a sudden high fever and flu-like symptoms that appear 4-7 days after infection with a dengue mosquito. Other signs and symptoms include a severe headache, especially behind the eyes, joint and muscle pain, nausea, vomiting, a rash, and swollen glands.
In some cases, people recover from the fever on their own, but some can progress to severe dengue fever, known as dengue hemorrhagic fever. Symptoms such as nosebleeds, blood in the vomit, blood in the stool, shortness of breath, cold and clammy skin, especially on the extremities, are observed. During the next, i. H. In the second phase, the virus attacks the vasculature (blood vessels) and causes the capillaries to leak fluid into the space around the lungs known as pleural effusion or ascites. If left untreated, it can worsen and become fatal to your health.
Interpretation of Dengue NS1 Antigen, IgG and IgM results
interpretations
result in the index | observations |
Negative (<0.9) | No detectable dengue NS1 antigen. The result does not rule out dengue infection. An additional sample should be tested for IgG and IgM serology after 7 to 14 days. |
False (0.9-1.1) | Repeat the sample after 1 week |
Positive (>1.1) | Presence of detectable dengue NS1 antigen. Dengue IgG and IgM serological assays should be performed on follow-up samples 5 to 7 days after fever onset to confirm dengue infection. |
Use:It is recommended to prepare NS1 antigen by ELISA in the first 5 days of fever. After fever persisting for 7 to 10 days, the recommended test is dengue IgG and IgM antibodies by ELISA.
ANTIBODIES DETECTED | OBSERVATIONS |
IgM | primary dengue |
IgM and IgG | Late primary / early secondary dengue fever |
IgG | Secondary/past dengue |
Answers to patient concerns and frequently asked questions (FAQs) about Dengue NS1 Antigen, IgG and IgM
Frequently asked questions about Dengue NS1 Antigen, IgG and IgM
Q
What are the symptoms of dengue fever?
Dengue fever takes about 3-7 days to show its effects. Sometimes the infection remains asymptomatic (without symptoms), but most people develop classic dengue. Symptomatic patients become acutely febrile (febrile) and may develop severe musculoskeletal pain, headache, retroorbital pain, and a transient macular rash, which is most common in children. Children and young adults remain at increased risk of developing dengue hemorrhagic fever and dengue shock syndrome, particularly after repeated infections with a new dengue virus serotype.
Q
Is there a vaccine against dengue?
No, there is no vaccine against dengue.
Q
How is the blood sample taken?
The doctor will take a blood sample from your arm. The blood collection site is cleaned with an isopropyl alcohol swab. A small needle with a tube attached is then inserted to collect blood. Once enough blood has been drawn for testing, the needle is withdrawn. The site is then covered with gauze.
Q
Are there any risks associated with blood collection?
Therefore, there is no risk, but in some cases bruising, bleeding and infection may occur at the puncture site. In very few cases, the vein may swell after the blood has been taken.
Q
What are the clinical forms of dengue fever?
Types of dengue fever include dengue fever or breakbone fever without serious complications, dengue hemorrhagic fever with bleeding, low blood platelets, and fluid (plasma) loss, and dengue shock syndrome with low blood pressure.
Q
Is there a specific treatment for dengue?
No, there is no specific treatment or antiviral medication for dengue. Available treatment is mainly supportive and based on observation of bleeding and circulatory abnormalities and the results of laboratory tests (eg, electrolytes, platelets, and hemoglobin).
Q
What is the advantage of detecting dengue NS1 antigen instead of dengue antibodies?
Detection of dengue NS1 antigen helps diagnose current infection within the first week of illness (during the fever phase). However, the detection of IgM antibodies indicates a possible current or recent infection (can be positive if the infection has occurred within the last 2-3 months). The diagnosis of a current infection by dengue NS1 is important for the medical treatment of acute fever. It has been observed that the detection of Dengue NS1 is much more reliable and takes less time than the IgM which takes between 6 and 10 minutes to display results.
+ more
tests included(3 exams)
Dengue IgG and IgM(includes 2 tests)
Dengue IgM antibodies
Dengue IgG antibodies
Dengue-NS1-Antigen
Provided by 1 laboratory
Often booked together
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Use:It is recommended to prepare NS1 antigen by ELISA in the first 5 days of fever. After fever persisting for 7 to 10 days, the recommended test is dengue IgG and IgM antibodies by ELISA.
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\\norte ANTIBODIES DETECTED \\norte | \\norte\\norte OBSERVATIONS \\norte | \\norte
\\norte IgM \\norte | \\norte\\norte primary dengue \\norte | \\norte
\\norte IgM and IgG \\norte | \\norte\\norte Late primary / early secondary dengue fever \\norte | \\norte
\\norte IgG \\norte | \\norte\\norte Secondary/past dengue \\norte | \\norte
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\",\"Symptoms\":\"
Dengue antigen NS1, IgG and IgM test is performed when high fever occurs within 2 weeks of travel to an area where dengue outbreak is occurring or when dengue fever is endemic.
\\norte
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The Dengue NS1, IgG and IgM antigen test measures dengue virus or antibodies produced in response to dengue infection. Dengue is a viral infection transmitted to humans by mosquitoes that live in tropical and subtropical climates and are responsible for transmitting the virus.
\\norte
According to the Centers for Disease Control and Prevention (CDC), dengue infections have been reported in more than 100 countries in parts of Africa, the Americas, the eastern Mediterranean, the western Pacific Caribbean and Southeast Asia.
\\norte
According to the WHO (World Health Organization), dengue is a rapidly onset infectious disease. The number of cases and countries affected by dengue is increasing significantly. With 75% of cases showing no symptoms, the true number is unknown, but the annual number of dengue infections reaches approximately 390 million.
\\norte
Most affected people develop no symptoms or only mild illness when exposed to any of the four dengue virus serotypes. Should a patient develop symptoms, the prognosis is good for a full recovery within a few weeks.
\\norte
Common initial symptoms are a sudden high fever and flu-like symptoms that appear 4-7 days after infection with a dengue mosquito. Other signs and symptoms include a severe headache, especially behind the eyes, joint and muscle pain, nausea, vomiting, a rash, and swollen glands.
\\norte
In some cases, people recover from the fever on their own, but some can progress to severe dengue fever, known as dengue hemorrhagic fever. Symptoms such as nosebleeds, blood in the vomit, blood in the stool, shortness of breath, cold and clammy skin, especially on the extremities, are observed. During the next, i. H. In the second phase, the virus attacks the vasculature (blood vessels) and causes the capillaries to leak fluid into the space around the lungs known as pleural effusion or ascites. If left untreated, it can worsen and become fatal to your health.
\\norte
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